In the last few years, cannabis has become a mainstream holistic medicine with many new users hopping on the train daily. With hundreds of different products to choose from, it may be a bit of a shock to figure out what’s best to try first. Growing in popularity for their ease of use, reliability and precise measurement, cannabis tinctures are an easy way to medicate discreetly. Different combinations of CBD to THC ratio will produce different effects that garner benefits for a wide variety of ailments.

With cannabis, there is no single ratio, or strain or concentrate that’s right for everyone. Every single person’s sensitivity to THC is a key factor in determining the appropriate ratio and dosage for effective usage.

Related: Cannabis Tinctures – A Manual of How to Use and Make Weed Tinctures

THC vs CBD Explained

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The two main cannabinoids can exert significantly different effects, both alone or combined in different proportions. This difference is becoming a central argument in understanding any medical benefit of cannabis, and it’s also an important issue to consider if you just want to “fine tune” your high.

An important difference between CBD and THC stays in the biochemical mechanisms by which these slightly different molecules actually bind with animals’ cannabinoid receptors.

THC binds well with a specific neuronal receptor named CB1, while CBD binds mostly with the receptor CB2. CBD reduces or “antagonizes,” some of the effects of THC like anxiety, paranoia, tachycardia, and possibly the high itself, by partially blocking CB1 receptors.

THC is believed to be responsible for most of cannabis’s sleep-inducing effects. On the other hand, studies suggest CBD acts to promote wakefulness.

Research on the benefits of tetrahydrocannabinol and cannabidiol in isolation is pretty clear: THC demonstrates analgesic, anti-emetic, and anti-inflammatory properties. CBD showed similar actions, plus anti-psychotic, anti-seizure, and anti-anxiety properties.

Clinical research on the simultaneous use of THC and CBD is just at its first stages. However, people reported better effects and less anxiety with hybrids containing a balanced proportion of CBD and THC than using strains with high THC alone.

It also seems that CBD enhances THC’s painkilling and anticancer properties, while both CBD and THC stimulate neurogenesis, the creation of new cells in the nervous system.

A common therapeutic strategy seems to be administering consistent and measurable doses of CBD plus as much THC as a person is comfortable with. Some conditions seem to respond well to a small dose of a CBD with little THC, while others benefit more from a balanced ratio around 1:1.

Different CBD:THC ratios can also be used at different times of the day. What follows is a rough description of the effects for each one of the significant CBD to THC ratios that people are today looking for, together with a selection of the corresponding cannabis genetics.

THC and CBD Ratio – 1:0

THC only tinctures will result in the most psychoactive, which can be good or bad. High amounts of THC can result in euphoria, uplifting mood, dizziness, and plenty of laughter. While these effects are desirable, excess amounts can lead to paranoia and anxiety.

As cannabinoids naturally occur together in different percentages, there are no strains with 0% of CBD. Some hybrids are close to this ratio, though. For example, Gorilla Glue by Zamnesia has a THC content of 25%, while Girl Scout Cookies is loaded with 22% of THC.

THC and CBD Ratio – 2:1

Although the psychoactive effects aren’t as pronounced, A 2:1 THC to CBD ratio can have great therapeutic benefits. CBD buffers the effects of THC, allowing for a higher dosage of THC without anxiety and paranoia.

A powerful sativa-dominant strain with a strong THC content and high amount of CBD is the feminized Sour Amnesia Haze by Royal Queen Seeds, which is commonly used as a medical strain.

THC and CBD Ratio – 1:2

The extra intake of CBD eliminates the euphoric rush, dizziness, and any other side effects of THC. Those who are often negatively affected by THC’s psychologically properties will be able to use this product and receive the THC benefits.

This product is perfect for those who need to medicate throughout the day but don’t want to receive any noticeable physical effects.

THC and CBD Ratio –  1:1

Research so far seems to have found that the 1:1 THC to CBD ratio provides the most therapeutic relief across wide categories of ailments, with just minor side effects.

This proportion between cannabinoids is having the best effect on sleep, pain and muscle spasms reduction, and it is under research for the treatment of autism, cancer, fibromyalgia, and skin diseases. The relaxation comes with very light high effect and little euphoria.

THC and CBD Ratio – 0:1

A CBD tincture means there is no THC present. The most noticeable CBD tincture effect is an overall sense of well being. Not a euphoria or bliss, but a relaxing feeling.

A full-CBD strain can lift the mood and bring many other benefits to our mind, health and well-being.

Cannabidiol is getting widely recognized as an effective anti-psychotic and relaxing compound, both on a central and peripheral level, with no side effects. Initial lab and clinical research tests are indicating enormous potential applications for CBD in medicine – though there is still a way to go.

If you’d like to try out some tinctures, enter our shop for our full selection of cannabis tinctures.